Gluco-engineered antibody-drug conjugates

摘要

A method of preparing an effector moiety-conjugated antibody, or antigen-binding fragment thereof, comprising the steps of: (a) reacting a cytidine monophosphate-sialic acid derivative (CMP-sialic acid) with a glucan of an antibody, or antigen-binding fragment thereof, to form a sialic acid …

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