工艺装备韩国已授权

Fc containing polypeptides with altered glycosylation and reduced effector …

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申请人젠자임 코포레이션

发明人클라크 팬

公开号KR102426488B1

授权号KR102426488B1

申请日2013-09-12

公开日2022-07-28

授权日2022-07-28

摘要

Binding polypeptides (eg, antibodies) and drug conjugates thereof comprising an Fc domain with an altered glycosylation profile and reduced effector function are provided herein. In certain embodiments, the Fc domain comprises an asparagine residue at amino acid position 298 according to EU …

Fc containing polypeptides with altered glycosylation and reduced effector &hellip;

摘要

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Fc containing polypeptides with altered glycosylation and reduced effector …